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CD BioGlyco Constructures a Glycoengineered P. pastoris Expression System for Research UseCD BioGlyco, with years of experience in glycoengineering, has solved a large number of shortcomings of the expression systems and brought customers high-quality cell lines to produce glycoproteins. Recently, the company established a glycoengineered P. pastoris expression system which overcomes the excessive glycosylation and the final glycoprotein produced has a uniform...0 Commentaires 0 Parts 154 Vue 0 Aperçu
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Inhibiting metabolic regulators in specific immune cells may increase inflammation in the bodyTransfer lipopolysaccharide activates monocytes through TLR4, which is thought to increase the risk of cardiovascular disease in HIV-infected individuals. Recently, in a study published in Communications Biology entitled "mTOR regulation of metabolic limits of LPS-induced monocyte inflammatory and procoagulant responses," scientists from the State University of New York at Upstate Medical...0 Commentaires 0 Parts 154 Vue 0 Aperçu
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Protheragen Obesity Announces Full Preclinical Services and Research Products for Obesity Drug DevelopmentDeveloping a new obesity drug requires multiple steps: target validation, pharmacokinetic studies, safety assessments, and more. Protheragen Obesity is a Contract Research Organization (CRO) that provides exactly these services, with a focus on the preclinical stage. The company recently announced its full range of service offerings and research products. According to its website,...0 Commentaires 0 Parts 160 Vue 0 Aperçu
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The Preclinical Foundation: How Obesity Models Drive Therapeutic BreakthroughsThe global escalation of metabolic disorders has transformed obesity from a secondary health concern into a primary clinical challenge, necessitating a more sophisticated approach to pharmaceutical intervention. While the ultimate goal of any therapeutic is successful human application, the high rate of attrition in clinical trials underscores the critical need for a robust preclinical...0 Commentaires 0 Parts 155 Vue 0 Aperçu